How it works
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Take the health questionnaire
100% online and confidential health intake form
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Get your prescription
All prescriptions overseen by fully licensed and insured physicians
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Get your meds
Fast free delivery from our accredited pharmacies
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Overview
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Benefits
What is Metformin?
Metformin is a well-known oral medication traditionally used to manage type 2 diabetes. In recent years, it has gained recognition in longevity and anti-aging medicine due to its impact on insulin sensitivity, mitochondrial health, inflammation, and cellular aging. As a caloric restriction mimetic, Metformin is now widely used off-label to support metabolic health, fat loss, and cellular resilience, with potential to reduce age-related diseases and improve health span.
Benefits:
- Enhances insulin sensitivity and stabilizes blood sugar
- May reduce visceral fat and improve body composition
- Supports mitochondrial function and metabolic flexibility
- May reduce the risk of age-related diseases (heart disease, cancer, cognitive decline)
- Activates cellular repair pathways (AMPK, autophagy)
How does it work?
Metformin targets multiple aging-related pathways through metabolic regulation and mitochondrial support:
- AMPK Activation
• Metformin activates AMP-activated protein kinase (AMPK), a key energy sensor that promotes fat oxidation, glucose uptake, and mitochondrial biogenesis—mimicking the effects of fasting. - Insulin Sensitivity & Glycemic Control
• It lowers circulating insulin and glucose levels, helping reduce systemic inflammation and oxidative stress, two hallmarks of aging and metabolic decline. - mTOR Pathway Modulation
• By inhibiting the mTOR pathway, Metformin slows down cellular overgrowth and supports autophagy—a crucial anti-aging process for cellular cleanup and repair.
Your Peers Approve. See Why
- JJustinReviewingDHH-BI recommend this productRated 5 out of 5 stars3 weeks agoProfessional the entire process feels
I value how professional the entire process feels. Notifications come on time, the portal is easy to navigate, and I know exactly when billing happens. It gives peace of mind.
- AAllisonReviewingDHH-BI recommend this productRated 5 out of 5 stars3 weeks agoThe dashboard feels simple and secure
The dashboard feels simple and secure. Managing my info and viewing past orders is straightforward, and I appreciate how transparent the policies are
- MMathewReviewingDHH-BI recommend this productRated 5 out of 5 stars3 weeks agoNice products
What I like most is how clear and organized everything is. From sign-up to checkout, the site explains every step. I never felt lost or confused.
- JJonathanReviewingDHH-BI recommend this productRated 5 out of 5 stars3 weeks agoThe portal is really user-friendly
The portal is really user-friendly. I can log in anytime to check the status of my orders and updates from the medical team. It saves me a lot of time compared to making clinic visits.
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